Ohio River Road Trip Itinerary
Embark on an unforgettable road trip along the Ohio River! This amazing journey starts in Pittsburgh, Pennsylvania, and ends in St. Louis, Missouri, covering a total distance of 1773km. The best time to make this trip is during the summer, when the weather is warm and the roads are in excellent condition.
Along the way, you will pass through the historic towns of Marietta, Ohio, Portsmouth, Ohio, Louisville, Kentucky, and Cairo, Illinois. Each town offers its own unique charm, from historic sites and monuments to local restaurants and shops. Marietta is home to the Ohio River Museum, Portsmouth has a vibrant music scene, Louisville is home to the iconic Kentucky Derby, and Cairo is located at the confluence of the Ohio and Mississippi Rivers.
This road trip is perfect for anyone looking for a memorable experience at a moderate budget. You can easily complete the trip in 10 days, giving you plenty of time to explore the sights and sounds of the Ohio River Valley. With its stunning scenery and rich history, the Ohio River Road Trip is an experience that you won't soon forget.
10
number of days
1,773 km
route length
fair
budget
family
good for
on the right
traffic direction
low
accident level
START
Pittsburgh
Distance 1,773 km
Driving time 25.0 h
Pace: fast
532.0 kWh
Airports
PIT
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Pittsburgh, Pennsylvania is the perfect starting point for your "Ohio River Road Trip". As a world-class city along the Allegheny, Ohio and Monongahela Rivers, Pittsburgh offers a wealth of attractions, activities and experiences. Start your visit at the iconic Point State Park, located at the confluence of the rivers, and take in the panoramic skyline views. From there, head to the nearby Carnegie Museum of Natural History to explore the area's cultural and historical roots. Other must-see attractions include the Andy Warhol Museum, the National Aviary and the Duquesne Incline.
If you're flying to Pittsburgh, the closest international airport is the Pittsburgh International Airport (PIT). The airport offers a variety of car rental services, so you can easily get on your way.
No matter how you choose to explore Pittsburgh, you won't be disappointed. Be sure to plan enough time to take in all the city has to offer before your Ohio River Road Trip begins.
1
Pittsburgh
- Marietta
Distance 219 km
Driving time 3.0 h
Pace: fast
65.7 kWh
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Are you ready for an unforgettable road trip? Start in Pittsburgh, United States and drive through Steubenville and end in Marietta. Along the way, you'll be able to explore the historical sites and attractions in these cities. The entire journey is only 136 miles and it will take you fewer than three hours to complete.
In Pittsburgh, you can visit the Carnegie Museum of Natural History, the Carnegie Science Center, and the Andy Warhol Museum. In Steubenville, you can explore the Historic Fort Steuben and the Ohio River Museum. And in Marietta, you can visit the Campus Martius Museum, the Ohio River Museum, and the Castle.
Make sure to take your time and enjoy the sights and attractions along the way. There is much to explore! For more information about attractions, accommodation options, recommended restaurants, and campsites along the route, please refer to the Itinerary of this stage. Have a great journey!
Marietta - United States - North America - Road Trip - commons.wikimedia.org
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2
Marietta
- Galliopolis
Distance 165 km
Driving time 2.5 h
Pace: fast
49.6 kWh
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Start your road trip from Marietta, United States and travel to Gallipolis, a journey of 103 miles that should take you no more than 3 hours. On your way, you will be able to explore some of the most interesting places in the area.
In Marietta, make sure to visit the Campus Martius Museum of the Northwest Territory, the oldest museum in the state, and the Ohio River Museum, where you can learn all about the area’s history and culture.
Once you reach Gallipolis, you can enjoy the beauty of the Ohio River at the Gallipolis City Park and take a stroll through the Gallia County Historical Museum.
This is only one stage of a larger tour, and more information about attractions, accommodation options, recommended restaurants and campsites along the route is available in the Itinerary of this stage. So, get ready for an amazing road trip experience!
Galliopolis - United States - North America - Road Trip - Wikimedia Commons
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3
Galliopolis
- Portsmouth
Distance 138 km
Driving time 1.9 h
Pace: fast
41.5 kWh
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Are you planning a road trip? Then you should definitely include a stop in Gallipolis and Portsmouth! The two cities are only 86 miles apart and the drive takes less than two hours. Gallipolis, located in the Ohio River Valley, is the oldest city in the state and famous for its historical sites. Make sure to visit the Ohio River Museum to learn about the area’s history and the Fife Opera House, a restored Victorian-era theater. Portsmouth is also home to a range of historical sites, including the Shawnee State Park and the Portsmouth Earthworks. Don’t forget to take in the breathtaking views of the Ohio River while you’re there! For more information about attractions, accommodation options, recommended restaurants, and campsites along the route, check out the “Itinerary” section of this stage.
Portsmouth - United States - North America - Road Trip - Flickr
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4
Portsmouth
- Cincinnati
Distance 188 km
Driving time 2.5 h
Pace: fast
56.5 kWh
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Are you ready for a thrilling road trip from Portsmouth to Cincinnati? This 117mi journey will take you less than 3 hours and you will have the opportunity to explore some of the most interesting places in these two cities.
In Portsmouth, you should definitely visit the Children’s Museum of Southern Ohio, the Scioto County Welcome Center, and the Shawnee State Park. The Children’s Museum of Southern Ohio is a great place for children and adults alike, offering a variety of interactive exhibits and activities. The Scioto County Welcome Center is an excellent place to get information about the area, while Shawnee State Park is a great spot to take a break and enjoy the natural beauty of the area.
In Cincinnati, you should visit the Cincinnati Zoo and Botanical Garden, the National Underground Railroad Freedom Center, and the Cincinnati Museum Center. The Cincinnati Zoo and Botanical Garden is one of the oldest zoos in the United States and is home to a variety of animals and plants. The National Underground Railroad Freedom Center is a great place to learn about the history of slavery in the United States. The Cincinnati Museum Center is an excellent place to explore the history of the city.
Make sure to check out the Itinerary of this stage for more information about attractions, accommodation options, recommended restaurants, and campsites along the route. Have a great trip!
Cincinnati - United States - North America - Road Trip - Wikipedio - Wikipedia
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5
Cincinnati
- Louisville
Distance 252 km
Driving time 3.6 h
Pace: fast
75.6 kWh
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Embark on a 157-mile journey from Cincinnati to Louisville, a road trip that will take you less than 4 hours. Start your journey in Cincinnati, a city known for its amazing parks, art galleries, and the Cincinnati Zoo. Take a break in Corydon, Indiana, the state's first capital. Here you can visit the Historic Corydon Capitol State Historic Site, a museum dedicated to the history of the state. Afterward, make your way to Louisville, a city known for its vibrant nightlife and its many attractions, such as the Louisville Slugger Museum & Factory, Louisville Zoo, and the Muhammad Ali Center. Don't miss the opportunity to explore the city's beautiful parks, such as Waterfront Park and Cherokee Park. For more information about attractions, accommodation options, recommended restaurants, and campsites along the route, please refer to the Itinerary of this stage.
Louisville - United States - North America - Road Trip - www.flickr.com
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6
Louisville
- Evansville
Distance 248 km
Driving time 3.6 h
Pace: fast
74.3 kWh
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Are you ready for an exciting road trip from Louisville to Evansville? This 154 mile journey will take you less than 4 hours and you will get to experience some of the most interesting places in the area.
In Louisville, you can start your trip by visiting the Louisville Slugger Museum & Factory. Here you can learn about the history of baseball and see the factory where the bats are made. You can also take a guided tour of the museum and factory.
As you continue your journey to Evansville, you can make a stop at the Falls of the Ohio State Park. Here, you can explore the fossil beds and learn about the history of the area. You can also enjoy the scenic views of the Ohio River.
Finally, you can end your journey in Evansville by visiting the Angel Mounds State Historic Site. This is a Native American site that dates back to 1000 AD. Here, you can explore the mounds, walk the trails, and learn about the culture of the Native Americans.
For more information about attractions, accommodation options, recommended restaurants, and campsites along the route, you can check the “Itinerary” of this stage. So, what are you waiting for? Get ready for an unforgettable road trip from Louisville to Evansville!
Evansville - United States - North America - Road Trip - Wikimedia Commons
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7
Evansville
- Cairo
Distance 300 km
Driving time 4.2 h
Pace: fast
90.0 kWh
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Welcome to the Evansville-Cairo road trip stage! This is one of the most exciting stages of your larger tour, and you are sure to be delighted by the sights and experiences you will find along the way. The route is 186mi long, and takes less than 5 hours to drive.
In Evansville, you can visit the Evansville Museum of Arts, History and Science, the Angel Mounds State Historic Site, and the Mesker Park Zoo and Botanic Garden.
Once you reach Cairo, you can explore the Cairo Historic District, the Cairo Public Library, and the Cairo National Cemetery.
More information regarding attractions, accommodation options, recommended restaurants, and campsites along the route is available in the "Itinerary" of this stage. Enjoy your journey!
Cairo - United States - North America - Road Trip - Wikimedia Commons
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8
Cairo
- St. Louis
Distance 263 km
Driving time 3.7 h
Pace: fast
78.9 kWh
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Welcome, road-trippers! Prepare yourselves for an amazing journey from Cairo to St. Louis, a distance of 163mi that can be driven in fewer than 4 hours.
First, you will visit Cairo, an amazing city in the United States, known for its beautiful architecture, historical monuments, and lush parks. Make sure to visit the Cairo Public Library, the Cairo Historical Museum, and the Cairo City Park.
Then, you will travel to St. Louis, a city full of attractions and activities. From the iconic Gateway Arch to the Saint Louis Zoo, there are many places to explore. Don't miss the Missouri Botanical Garden, the Cathedral Basilica of St. Louis, and the City Museum.
This is one of the stages of a larger tour, and more information regarding attractions, accommodation options, recommended restaurants, and campsites along the route is available in the "Itinerary" of this stage.
We hope you have a great time during your journey from Cairo to St. Louis!
St. Louis - United States - North America - Road Trip - Wikimedia Commons
St. Louis - United States - North America - Road Trip - Pixabay
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St. Louis
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St. Louis is the perfect destination for those looking to end their Ohio River Road Trip in style. Located in the heart of the United States, this vibrant city offers a wealth of attractions and activities for visitors to enjoy. From the iconic Gateway Arch to the lush Forest Park, St. Louis offers something for everyone.
For those looking to explore the city’s history, the Gateway Arch is a must-see. Built in 1965, the mammoth stainless-steel structure stands 630 feet tall and is an iconic symbol of the city. Visitors can take a tram ride to the top of the Arch to get a panoramic view of the city.
For nature lovers, Forest Park is the perfect spot for a peaceful stroll. This 500-acre park is home to a number of attractions including the St. Louis Zoo, the St. Louis Art Museum, and the Missouri History Museum.
For those who prefer to explore the city’s cultural attractions, St. Louis has plenty to offer. The city is home to a vibrant music and arts scene, with a number of venues offering concerts and performances. Visitors can also explore the many galleries and museums that dot the city.
For travelers arriving by air, the closest international airport is Lambert-St. Louis International Airport (STL). From here, visitors can easily rent a car and begin their Ohio River Road Trip adventure.
Whether you’re looking for a cultural experience or a relaxing getaway, St. Louis is the perfect destination to end your Ohio River Road Trip.
St. Louis - United States - North America - Road Trip - Wikimedia Commons
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Ohio River Road Trip at a glance
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Start:
Pittsburgh
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End:
St. Louis
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Distance:
1,773 km
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Stay:
10 days
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Getting there:
Pittsburgh International Airport (PIT)
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When to drive:
May, June, July, August, September, October
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More info:
More info you can find in the "Itinerary" section at each stage.
Before you set off
Embark on the quintessential American adventure with the Ohio River Road Trip, stretching from the cosmopolitan streets of Pittsburgh, Pennsylvania, to the iconic Gateway Arch of St. Louis, Missouri. Covering a distance of approximately 1,773 kilometers (1,102 miles), this journey not only links a series of charming historic towns and lush scenic landscapes but also weaves through a tapestry of rich cultural tapestries reflective of the heartland of the United States.
Key Destinations and Top Sights:
- Pittsburgh, PA: Begin in a city where the confluence of the Allegheny, Monongahela, and Ohio Rivers underscores its historical significance. Pittsburgh is home to the Andy Warhol Museum and the Phipps Conservatory and Botanical Gardens, offering a glimpse into a thriving arts and green scene.
- Marietta, OH: Step into the past with a visit to the Campus Martius Museum, a preserved fortification and museum that tells the tale of Ohio's early settlers. The nearby Ohio River Museum delves into the river's pivotal role in American history.
- Portsmouth, OH: Discover a community with a passion for the arts, exemplified by the floodwall murals that depict the town's history. This city's music scene thrives with festivals and venues celebrating Appalachian culture.
- Louisville, KY: Experience the thrill of the Kentucky Derby, the longest continuously held horse race in America, or delve into the urban bourbon trail. The city's Muhammad Ali Center pays homage to the legendary boxer's legacy.
- Cairo, IL: At the confluence of the Ohio and Mississippi Rivers, Cairo's strategic location shaped its historical importance, once a bustling river port and a critical supply depot during the Civil War.
Best Time to Go:
The journey is most pleasant from late spring to early fall, with May through September offering ideal conditions for enjoying the lush landscapes and outdoor activities. Fall foliage along the Ohio River can be particularly breathtaking.
Potential Risks:
Summer Trips invite the risk of thunderstorms and high humidity, while winters can present tricky driving conditions due to snow and ice. It's advisable to check weather forecasts and Road conditions regularly, and prepare for the season's challenges.
Interesting Facts for Roadtrippers:
- The Ohio River is the site of the annual Great Steamboat Race, a tradition dating back to 1963, where historic riverboats race along the Louisville waterfront.
- A 10-day itinerary not only provides a relaxed pace but the opportunity to immerse in each location, perhaps catching a local event or festival.
- The region's history is intertwined with the stories of the Native American tribes, westward expansion, and the Underground RailRoad.
A good choice for:
The Ohio River Road Trip is an unforgettable exploration of America's cultural and historical heartbeat. With each mile, Roadtrippers encounter landmarks that shaped the nation, natural beauty that inspires awe, and communities that embody the enduring spirit of the American Midwest.
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